Erythropoietin treatment alleviates ultrastructural myelin changes induced by murine cerebral malaria
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چکیده
منابع مشابه
Systemic and Cerebral Vascular Endothelial Growth Factor Levels Increase in Murine Cerebral Malaria along with Increased Calpain and Caspase Activity and Can be Reduced by Erythropoietin Treatment
The pathogenesis of cerebral malaria (CM) includes compromised microvascular perfusion, increased inflammation, cytoadhesion, and endothelial activation. These events cause blood-brain barrier disruption and neuropathology and associations with the vascular endothelial growth factor (VEGF) signaling pathway have been shown. We studied this pathway in mice infected with Plasmodium berghei ANKA c...
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ژورنال
عنوان ژورنال: Malaria Journal
سال: 2012
ISSN: 1475-2875
DOI: 10.1186/1475-2875-11-216